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PhamExtracta INSIGHTS, News and Expertise

Women’s Wellbeing After Menopause: Triumphing Over Genitourinary Syndrome with Zantogin® Gel

To address Genitourinary Syndrome of Menopause (GSM), PharmExtracta developed Zantogin® vaginal gel, a patented medical device containing highly purified plant extracts and hyaluronic acid to provide healing, re-epithelizing, and moisturizing effects.
A recent study conducted at Sapienza University of Rome demonstrates the positive impact of Zantogin® Gel on post-menopausal women suffering from GSM. Study results show not only a significant improvement in GSM symptoms but also a remarkable decrease in dyspareunia and improvements in the Vaginal Health Index, Female Sexual Distress Scale, and Regular Sexual Activity.

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Hepa G®: Revolutionizing Liver Health for NAFLD Patients

Non-Alcoholic Fatty Liver Disease (NAFLD) is a prevalent and potentially serious condition affecting millions worldwide. Often diagnosed alongside lifestyle recommendations, it is crucial to explore alternative interventions to improve liver health and prevent the progression of the disease.
Hepa G®, with its unique formulation and patent protection, emerges as a promising solution to enhance liver health, offering new hope and possibilities for individuals facing the challenges of NAFLD.

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Brevicillin®: Safeguarding Gut Health During Therapy with Amoxicillin or Amoxicillin/clavulanate

Antibiotics remain a fundamental tool crucial for saving lives. However, their overuse or misuse can adversely affect the gut microbiota, leading to both short-term and long-term consequences.
Brevicillin® is a novel probiotic that features the strain Bifidobacterium breve PRL2020, specifically identified to mitigate the detrimental effects of therapies involving amoxicillin and amoxicillin/clavulanic acid. The unique intrinsic resistance to these antibiotics of Bifidobacterium breve PRL2020 ensures a completely safe profile.

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Enhancing Therapeutic Response in Gastroesophageal Reflux Disease: The Role of Mirgeal® gel

Over 40% of patients suffering from Gastroesophageal Reflux Disease still grapple with symptoms despite relying on proton pump inhibitors (PPIs). A dedicated review explores advanced therapies to support them, unveiling Mirgeal® gel as a revolutionary adjunctive treatment.
With unique ingredients like licorice extract and Mirtoselect®, Mirgeal® gel outperforms traditional options, providing lasting relief and transforming GERD care.

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Empowering Women with PCOS: The Sophy® Solution

PCOS poses challenges affecting various aspects of women’s lives, often hindered by limited treatment options and side effects from conventional therapies.
Sophy® addresses these issues by harnessing Berberine’s potential, with the innovative Berberine Phytosome® that enhances absorption, making Berberine 10 TIMES MORE bioavailable.
A recent clinical trial demonstrated remarkable results in just 3 months, including an 80% decrease in menstrual disorders, a 70% decrease in ovarian polycystosis, and a 55% decrease in acne.

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Exploring Crispact®: A Probiotic Perspective on Enhancing Assisted Reproductive Techniques

The rise in infertility rates has prompted the growth of ART procedures. A recent study assesses the potential role of Crispact® with Lactobacillus crispatus M247 in enhancing the success of ART for 160 infertile women undergoing various procedures.
Results in treated women show a 36% increase in positive pregnancy tests, 88% in D5 embryo transfers, and 67% more live births compared to the control group. These promising outcomes undoubtedly open up dialogue on Crispact®‘s role in fertility treatments.

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Nisatol®: Maximizing the Potential of Nigella Sativa Extract with a High 10% Thymoquinone Content

According to science, the benefits of Nigella sativa include anti-inflammatory, antioxidant, immune support, and more. However, when choosing a supplement based on this botanical, Thymoquinone concentration is crucial.
Nisatol® maximizes the potential of Nigella Sativa with a 10% Thymoquinone content. Furthermore, its unique formulation ensures optimal absorption, featuring enteric coating and Vitamin E to guard against oxidation.

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Berberol®: Exploring the Potential of the Berberine-Silymarin Synergy

Research shows that berberine with silymarin has better absorption than berberine alone. A 2018 meta-analysis focused specifically on studies examining this combination, and after evaluating 26 studies, only 5 studies on Berberol® were found to be eligible.
Berberol® is the most studied product containing a fixed combination of berberine and silymarin, which enables a much better absorption of berberine and unlocks its impressive potential to improve metabolic parameters.

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Fibradis®: Elevating Gut Health and Celebrated Excellence

Fibradis® is a revolutionary supplement addressing gut health and is a finalist at the NutraIngredients-Asia Awards, highlighting its commitment to innovation. It effectively targets gut dysbiosis symptoms and has shown remarkable results in clinical trials for IBS patients.
Its unique bipartite sachet makes it convenient for children, while its patented blend of fibers nourishes specific gut bacteria, restoring ideal balance. Fibradis® is not just a supplement: it’s a precision prebiotic transforming gut health, with plans to reach new markets.

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Unlocking Hope for Women with PCOS: Berberine Phytosome® Breakthrough

PCOS is a common endocrine disorder in women, which involves hormonal imbalances and metabolic issues and takes a toll on both physical and emotional well-being. Unfortunately, current treatments often have drawbacks.
A recent Italian study investigates the potential of Berberine Phytosome® to help PCOS-diagnosed women relieve their symptoms. Results are noteworthy, showing reduction in insulin resistance, improved hormonal profiles, reduced hyperandrogenism, and acne amelioration.

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Gabapral®: new precision psychobiotic that increases GABA production

GABA is an inhibitory neurotransmitter in the brain that helps regulate anxiety and stress responses. It is believed that increasing GABA levels in the brain may have a calming effect on the nervous system and potentially reduce anxiety and stress.
GABApral® is a new psychobiotic containing Bifidobacterium adolescentis PRL2019, a very unique strain that has shown a high capability of producing GABA both in vitro and in vivo and can therefore offer a help to individuals dealing with chronic anxiety, stress or associated problems.

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Preventing UTIs with Cranberry? It is possible with MonoSelect® Macrocarpon

Cranberry products have been used for several decades to prevent urinary tract infections (UTIs). Recently a Cochrane review has pointed out the mechanism underlying cranberry activity: the compounds known as Proanthocyanidins (PACs) interfere with the adhesion of bacteria, making it more difficult for them to cause an infection.
MonoSelect® Macrocarpon is a clinically tested supplement that helps prevent UTis thanks to its important content in PACs and the enteric coating that avoids the degradation by stomach acids.

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Lactobacillus crispatus M247: the only probiotic strain with studied activity against HPV

HPV infection can be worrying since some types of HPV are associated with the development of cervical cancer, so a rapid viral clearance is crucial to serenity.
Lactobacillus crispatus M247 is the only probiotic that has been studied for its capability of promoting HPV clearance. Moreover, it shows a very high colonization profile of the vaginal environment where it creates the ideal conditions to prevent vaginal infections from several pathogens.

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Looking for a winning strategy to reduce statin dosage? Berberol® is the answe

Looking for a winning strategy to reduce statin dosage? Berberol® is the answer

Statins are important drugs because of their effectiveness in lowering cholesterol. However, some people may experience adverse effects during the treatment, particularly when taking high dosages.
Berberol® can help in controlling high LDL cholesterol and may be recommended as complementary approach to statin therapy, to reduce the dosage by half while maintaining an optimal lipid level.

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Brevicillin®: birth of a new probiotic tool to serve as add-on treatment to Amoxicillin/Clavulanic acid

Brevicillin®: birth of a new probiotic tool to serve as add-on treatment to Amoxicillin/Clavulanic acid

Do you know that taking Amoxicillin/Clavulanic acid disrupts the gut microbiota and, particularly, causes a dramatic drop in Bifidobacteria?
This prompted us to search for a bifidobacterial strain that is able to resist to AMC and that could be developed in a probiotic supplement to be taken in conjunction with this antibiotic therapy.
Here comes the birth story Brevicillin®: the only probiotic containing the special strain Bifidobacterium breve PRL2020 with intrinsic resistance to AMC.

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Anxiety and Insomnia relief: 3 engineered extracts in just one formula as an alternative to benzos

Anxiety and Insomnia relief: 3 engineered extracts in just one formula as an alternative to benzos

Anxiety and Insomnia can significantly impair day-to-day functioning. To treat these conditions doctors may prescribe benzodiazepines, which are potent medications but unfortunately, have quite a few drawbacks.
Neurofast® has been shown to perform really well on anxiety and insomnia, similarly to benzodiazepines, but it is natural and side-effect free. It comes in three-layer tablets to create a more structured and effective combination of actions.

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Berberol®: Berberine made bioavailable to treat dysmetabolic patients straight to target

Berberol®: Berberine made bioavailable to treat dysmetabolic patients straight to target

Berberol® is the first food supplement containing berberine that overcame the issue of the very poor bioavailability of this botanical ingredient thanks to its patented formulation featuring Silymarin.
The effectiveness of this supplement in blood sugar and blood fat control has been confirmed by several studies according to which Berberol® could be a treatment option for different kinds of patients.

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Can a specific precision prebiotic help people with IBS?

Can a specific precision prebiotic help people with IBS?

Fibradis® is the only precision PREbiotic supplement containing a blend of fibers formulated to feed bacteria genus-specifically to promote the proliferation and colonization of bifidobacteria and lactobacilli in gut physiological proportions.
A study confirms the effectiveness of Fibradis® in reducing IBS symptoms.

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Lactobacillus crispatus: the gold standard probiotic for vaginal health

Lactobacillus crispatus: the gold standard probiotic for vaginal health

Lactobacillus crispatus has become famous for the protective role it plays against vaginal infections and other gynaecological problems.
Lactobacillus crispatus M247, taken orally, is able to efficiently colonize the vaginal environment and exert its protective activities. Moreover, it can be used as add-on to metronidazole and boric acid.

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How to ease acid reflux with a game-changer nutraceutical

How to ease acid reflux with a game-changer nutraceutical

Introducing Mirgeal® gel, innovative food supplement that rapidly relieves symptoms related to acid reflux performing better than alginate.
It features two botanical extracts able to protect against ulcers and re-epithelize gastric and esophageal mucosa with long-term benefits.

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